The medicines, their effectiveness, the various challenges of the condition

The experience of , the symptoms for each person suffering from PD can be different from another also for the same person each day could present with different challenges. Thing could go perfect a few days and suddenly there could come a day, when the medicine is ineffective, there is continuous pain through the day. With me, I get a peculiar pain in lower legs ( below the knee). On some weekdays when I am in office, the pain starts as the dose of levodopa reaches it end typically in every 3 to 4 Hours. As I  pop a pill again, the pain recedes.. This can be relatable to office environment, could be some amount of stress of being at the work place. But on some days, the pain in the legs persists even after taking the medication. Till now, I could only explain this with the following two reasons

• I may have inadvertently eaten some protein rich food which could have blocked levodopa to move up and cross the blood- brain barrier. to tackle this I shift my protein intakes to evening ( non-active period)
• The levodopa could not take effect due to constipation. It is a vicious cycle. Levodopa is needed to control the symptoms – Levodopa also creates constipation – Constipation block Levodopa from doing its work

I have been dealing with each day as it comes.. some good days some not so good days…